S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Yap1p	YJR104C	PubMed Lee J et al., J Biol Chem, 1999 Jun 4;274(23):16040-6	Indirect	Proteomics - wt vs TF mutant	Positive	S288c	15 minutes exposure to 0.2 mM H2O2 (SC growth medium)
		PubMed Dumond H et al., Mol Microbiol, 2000 May;36(4):830-45	Indirect	Microarray analysis - wt vs TF mutant	Positive	W303a	Exponential cells grown in galactose minimal medium followed by oxidative stress (0.4mM H2O2)
		PubMed Lee TI et al., Science, 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Haugen AC et al., Genome Biol, 2004;5(12):R95	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	Synthetic complete medium after 2h exposure to 100 microM AsIII (30.C).
		PubMed Lucau-Danila A et al., Mol Cell Biol, 2005 Mar;25(5):1860-8	Direct	ChIP	N/A	S288c	YPD medium + 20 mg/L benomyl
		PubMed Dubacq C et al., Mol Genet Genomics, 2006 Feb;275(2):114-24	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium + 200mM hydroxyurea
		PubMed Thorsen M et al., Physiol Genomics, 2007 Jun 19;30(1):35-43	Indirect	Microarray analysis - wt vs TF mutant	Positive	W303-1A	1.0 mM As(III), 1 h
		PubMed Tan K et al., Proc Natl Acad Sci U S A, 2008 Feb 26;105(8):2934-9	Direct	Chip-on-chip	N/A	S288c	SC medium + MMS (methylmethanesulfonate)
		PubMed Menezes RA et al., Biochem J, 2008 Sep 1;414(2):301-11	Indirect	RT-PCR - wt vs TF mutant	Positive	BY4741	2mM Na2HAsO or NaAsO2
		PubMed Salin H et al., BMC Genomics, 2008 Jul 15;0(0):33	Direct	Chip-on-chip	N/A	BY4742	YPD + Sodium selenite (1 mM), hydrogen peroxide (0.3 mM) or benomyl (20 microg/ml)
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 40 min
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 60 min
			Indirect	Microarray analysis - wt vs TF mutant	Negative	BY4742	YPD+1mM selenite 80 min
		PubMed Kelley R et al., PLoS Genet, 2009 May;5(5):e1000488	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	YPD 30.C 0.1 mM H2O2
		PubMed Reimand J et al., Nucleic Acids Res, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	YPD medium; mid-log phase
		PubMed Bleoanca I et al., J Biosci Bioeng, 2013 Dec;116(6):697-705	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	SC medium + EtOH 7.5%
		PubMed Pimentel C et al., Biochim Biophys Acta, 2014 Jun;1840(6):1977-86	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	2 mM CoSO4
		PubMed Zhang C et al., Yeast, 2016 Jan;33(1):5-19	Indirect	RNA-seq - wt vs TF mutant	Positive	S288c	SD medium + t-BHP + MMS
		PubMed da Silva SM et al., Biochim Biophys Acta Gen Subj, 2018 Oct;1862(10):2152-2161	Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4741	YPD + 2â€¯mM arsenic
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	YPD medium, 25.C