S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Hsf1p	YDL020C	PubMed Lee TI et al., Science, 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Hahn JS et al., Mol Microbiol, 2006 Apr;60(1):240-51	N/A		N/A	S288c	N/A
		PubMed Workman CT et al., Science, 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A
		PubMed Yamamoto N et al., Eukaryot Cell, 2008 May;7(5):783-90	Indirect	RT-PCR - wt vs TF mutant	Positive	HS170T	wt versus hsf1 R206S-H220R ( arginine to serine at residue 206 and histidine to arginine at residue 220) ESD media lacking uracil heat shock(temperature shift from 28.C to 37.C for 1h and then 48.C
		PubMed Hou J et al., FEMS Yeast Res, 2014 May;14(3):481-94	Indirect	Microarray analysis - wt vs TF overexpression	Positive	S288c	DTT inhibition
		PubMed de Jonge WJ et al., EMBO J, 2017 Feb 1;36(3):274-290	Direct	ChIP	N/A	S288C	SC medium
		PubMed de Jonge WJ et al., EMBO J, 2017 Feb 1;36(3):274-290	Indirect	RT-PCR - wt vs TF mutant	Negative	S288C	SC medium
		PubMed Pincus D et al., Mol Biol Cell, 2018 Dec 15;29(26):3168-3182	Direct	ChIP-seq	N/A	BY4741	YPDA (with 0.002% adenine), non-heat shock, 5Â´heat shock and 120Â´heat shock
			Direct	ChIP-seq	N/A	BY4741	YPDA (with 0.002% adenine), 5' heat shock
			Indirect	NAC-seq (nascent mRNA-sequencing)	Positive	BY4741	YPDA (with 0.002% adenine), 5' heat shock
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	YPD medium, 25.C