Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Protein Information

Protein Name Mth1p
Description Negative regulator of the glucose-sensing signal transduction pathway; required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation; MTH1 has a paralog, STD1, that arose from the whole genome duplication
Aminoacid Sequence
Download FASTA 
>MTH1 YDR277C
MFVSPPPATSKNQVLQRRPLESTNSNHGFASSLQAIPENTMSGSDNASFQSLPLSMSSSQ
STTSSRRENFVNAPPEYTDRARDEIKKRLLASSPSRRSHHSSSMHSASRRSSVAESGSLL
SDNASSYQSSIFSAPSTVHTQLTNDSSFSEFPNHKLITRVSLDEALPKTFYDMYSPDILL
ADPSNILCNGRPKFTKRELLDWDLNDIRSLLIVEKLRPEWGNQLPEVITVGDNMPQFRLQ
LLPLYSSDETIIATLVHSDLYMEANLDYEFKLTSAKYTVATARKRHEHITGRNEAVMNLS
KPEWRNIIENYLLNIAVEAQCRFDFKQRCSEYKKWKLQQSNLKRPDMPPPSIIPRKNSTE
TKSLLKKALLKNIQLKNPNNNLDELMMRSSAATNQQGKNKVSLSKEEKATIWSQCQAQVY
QRLGLDWQPDSVS* 
Regulon See Venn diagram regulon   
Documented targets See documented regulated genes
External source Open in SGD external link
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