Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name HRT1
Systematic Name YOL133W
Alias HRT2, RBX1, ROC1
Strain S288c
Description RING-H2 domain core subunit of multiple ubiquitin ligase complexes; subunit of Skp1-Cullin-F-box (SCF) that tethers the Cdc34p (E2) and Cdc53p (cullin) SCF subunits, and is required for degradation of Gic2p, Far1p, Sic1p and Cln2p; subunit of the Rtt101p-Mms1p-Mms22p ubiquitin ligase that stabilizes replication forks after DNA lesions; subunit of the Cul3p-Elc1p-Ela1p ubiquitin ligase involved in Rpb1p degradation as part of transcription-coupled repair
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>HRT1 YOL133W
ATGAGCAACGAAGTTGACAGGATGGATGTTGATGAAGATGAATCGCAAAATATTGCGCAA
AGCTCAAACCAAAGTGCGCCAGTGGAAACCAAAAAGAAGAGATTTGAAATTAAGAAATGG
ACCGCAGTGGCGTTTTGGTCATGGGATATAGCTGTTGACAACTGTGCTATTTGCAGGAAC
CATATAATGGAACCATGCATTGAATGCCAGCCAAAGGCCATGACGGACACTGATAATGAA
TGTGTAGCAGCCTGGGGTGTCTGTAATCACGCTTTCCATTTGCACTGTATTAATAAATGG
ATCAAGACAAGAGACGCATGCCCATTAGATAACCAACCTTGGCAGTTAGCAAGATGCGGT
AGGTGA
Promoter Sequence
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>HRT1 YOL133W
TACGGTAGTTGAAAATGTATATAGTTACACAAATGATTTATAATAGTGTGGTCATTGGGA
CGACGATGGAGGAGATTGTGATCCGGTTCTTAAGGTGTCCTGTATGCTGGTGAGTTTGTC
GTGTACCTGTTTGCATACTTGCTCGATCTCGCGAATTTCCCCGCGCTTGTATTCTAATTG
TTCTTCCAATAGCATAATAAGGGACTCTCGGGACTGATGGGGTCTGTACTCATTAAGTAG
GTGGTGAATATTGACAAGAATGGTCCTTATGTTCTCCACTTTGCGCTCATACATATCCGG
ATTTATGCTCAATACGCCGATGAGTTCCAAGTAATTTAGCAGGAGGGATTTCAATAGTTT
GCGTAGCTCTTGGATTTTGTATTGATAATTTGTGCTTTCGTTTTCTGTGGATTTCTTATA
AAGTTGGGTGAGTCCCATGCTCTCTAAATCGGGCAGTTGGTCCTTCACCTGCCATATACT
CCCAAACGCTCGGTACTGCTGATTTTTGGGCATGGGGGGTGGGATTAGGTAATCTAGCGC
ACATGTAATCTCCTCTTCACTGCCGCCGTTACTGTTATTTGGAGCCGTCTGCTTCGCACT
TGCGGCCTTCTTTTCTTTGTATTTTGGTAATTTTTCCAGATTGGACTGTGTGAAAAACTT
CACGTATGGGGGTGGAGGTGGGTACAAGGAGCTAACCTCATTACCAGGATCATTGGACAT
TTTTAGTTTGTGAATTTTTTTTTTACTAGCTTAAATTTGGGATATGAAACCTCTTTTATG
TCATATTTGCACGTCTAATGACCTGCCTGCTGAAAATGCAAGATTCGTTGTTTAAGTTCT
AACTAACATTTCGTATTTCGTGATAATAGTTTCTTTTAAAGGTGTGAAGAGGGAGATCAT
GAAACCCACAATAGACGTATGGGCTTCAATATGTGCAATGTTGGTTGCTACTAAATGTCT
TTCTCCAGTGGCAGAGAACTTTAAAGAGAAATAGTTCAAC
Chr coordinates Chr XV from 70325-70690
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