Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name TIF1
Systematic Name YKR059W
Alias eIF4A
Strain S288c
Description Translation initiation factor eIF4A; DEAD-box RNA helicase that couples ATPase activity to mRNA binding and unwinding; ATP hydrolysis accelerates the recruitment of mRNA during 48S preinitiation complex (PIC) assembly; ATPase activity stimulated by either eIF4G1 or by the PIC in an eIF3g and eIFGi subunit-dependent manner, independent of eIF4E and eIF4G; subunit of the mRNA cap-binding protein complex (eIF4F) with eIF4E and eIF4G; protein abundance increases in response to DNA replication stress
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>TIF1 YKR059W
ATGTCTGAAGGTATTACTGATATTGAAGAATCCCAAATTCAAACCAACTATGACAAGGTT
GTCTACAAGTTCGATGATATGGAATTGGACGAAAACTTGTTAAGAGGTGTTTTCGGTTAC
GGTTTCGAAGAACCATCTGCCATTCAACAACGTGCCATCATGCCTATTATTGAAGGTCAC
GATGTCTTGGCTCAAGCTCAATCTGGTACTGGTAAGACCGGTACCTTTTCCATTGCTGCT
TTGCAAAGAATTGACACCTCTGTCAAGGCTCCTCAAGCTTTGATGTTGGCTCCAACTAGA
GAATTGGCTTTGCAAATCCAAAAGGTTGTCATGGCTTTGGCTTTCCACATGGACATCAAG
GTCCACGCTTGTATCGGTGGTACTTCCTTTGTTGAAGACGCTGAAGGTTTGAGAGATGCT
CAAATCGTCGTTGGTACTCCAGGTCGTGTTTTTGACAACATCCAAAGACGTAGATTCAGA
ACTGACAAGATCAAGATGTTCATCTTAGATGAAGCTGATGAAATGTTGTCTTCTGGTTTC
AAGGAACAAATCTACCAAATTTTCACCTTACTTCCACCAACCACTCAAGTTGTTCTATTG
TCCGCCACCATGCCAAATGACGTCTTGGAAGTTACCACCAAATTTATGAGAAACCCAGTT
AGAATTTTGGTTAAGAAGGATGAATTGACTTTGGAAGGTATCAAACAATTCTACGTTAAT
GTTGAAGAAGAAGAATACAAATACGAGTGTTTGACCGATTTATACGACTCTATCTCCGTT
ACTCAAGCTGTCATCTTCTGTAACACCAGAAGAAAGGTCGAAGAATTGACCACTAAGTTA
AGAAACGACAAATTTACCGTTTCTGCCATCTACTCTGATTTACCACAACAAGAAAGAGAC
ACCATCATGAAGGAATTCAGAAGTGGTTCTTCCAGAATTTTGATCTCCACTGATTTGTTG
GCTAGAGGTATCGATGTCCAACAAGTTTCTTTGGTTATTAACTACGACTTACCAGCTAAC
AAAGAAAACTATATTCACAGAATCGGTAGAGGTGGTCGTTTCGGTAGAAAGGGTGTTGCC
ATCAACTTTGTTACTAACGAAGACGTTGGCGCTATGAGAGAACTAGAAAAGTTCTACTCC
ACTCAAATTGAAGAATTGCCATCCGACATCGCTACTTTGTTGAACTAA
Promoter Sequence
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>TIF1 YKR059W
GGAACTAAACAGCTCTTATAGCGTTGTGAGTACTCAAGCTGATAGCGATGAGCACCAAAA
TGCAGAAGAGGAGGATAGTACGACAGATAACGCTTCAAATTCTGGAGAAGAAAGCCACCT
CGATGATATAAGCACGGCCGCTTCTTCCAATAACAATGTAAGTAATCAACCAGATGGCAA
AAATTTTAGCAATTCTAAAGAAAATAATATCAGTGTCGAATCTAGCCCTTCAAATCCAGA
ACAGAAAAGGTCAACTGACAATATACAAAAACCAAGTGTTTCTACTAATGACTTACCAGA
CGACGTAGAACCACATACCTCTGTTGATGACAATATACAGTACTTAGAAAAAGACAAGGA
AGGTTATGAAGAATTTCTTCCGGACGTGTACGAGTCAAATGCAATCGATAACGAAGAAGA
ATTTTTTGATGACGATGCAAGAGATGCTACCGAAGGAGAAACGAAGACGAGTGCAGTTGC
AGATAAACAGGAGGATATGAAACTTACAGCAGAGGAAACCAACCAACCGCAACAAGAAAT
GCCCAACTTCAAATTTGACTGGGAGGACTCTGATTATCTATCCAAAGTAGAGAGGTGTTT
CCCTGATGATATTTTTGAGTATGCAGTAGAGTAAACTTCCACGCACATATTAGGAAAATT
AAAAGACATATCTATGTAAAGACCTTTTCGACTATACAAAAATGCATAACTATTCTATAT
ACATTCAAACTCGAAATTTACTTTAAAGGTTTATCAGCAACAACATCCGATGCTTGCTGT
TTATCTTTTCTCACCTCACAACGTTTATAGTGACTGAAAAATTTTTGCATTCTCACCTCG
TCTATTGAATGATGTGCTAAGAACTTGAGCTAACATCACAGAACAAAGGTATGAATATAC
GCAGCCCTGACATTTGTAGATTTTTTATTTGGTCTCTAGTCTTTTCTTTTCTTATTTTAT
AACAAATTCGTTAAACGGCCTCCTTCTAATTATATACAAG
Chr coordinates Chr XI from 554987-556174
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