Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
DPB11 Systematic Name
YJL090C Strain
S288c Description
DNA replication initiation protein; loads DNA pol epsilon onto pre-replication complexes at origins; checkpoint sensor recruited to stalled replication forks by the checkpoint clamp complex where it activates Mec1p; along with Rfa1p, binds to ultrafine anaphase bridges in mitotic cells and prevents accumulation of chromatin bridges by stimulating the Mec1p kinase and suppressing homologous recombination; ortholog of human TopBP1; forms nuclear foci upon DNA replication stress External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>DPB11 YJL090C
ATGAAGCCCTTTCAAGGAATAACATTTTGTCCGACTGCAATAAATAATGAAATCTTAGCT
AAAAAAATATCAAAGAAAATTATTAAGTTAGGAGGTATATTTTCTAAAGATTTGACCAGA
CAAGTTAATGTCCTTGTTGTTGGGTCCACCACCAATACAAACAAATTTAAATTTGCGGTG
AAGCATAGATTCGATATCATATTTATTGACATTCAAGCCATTGATGACATTTATCAGCTC
TGGCTGTCTGGAGAAAATATATTGCCGGACTCTAATACGGCAACAATGACAGGATCCACC
TATGAGATGCTGAAGATACTTTACCGGCGATTTTCGTTTAAATATTTGCATAACTTCAAT
ATCTTCATTGGCAGAATAACCGACACTAACATAACTTCCATCGATTCATTGGTTAGGAGT
ATTAAAAAGTTAGGGTGTTCTAGTTATAACTATCAAAACTTTGTAATCAAAGATACCTCT
TCACACAATGATGACGATGATCAAGGTCAGAATGGGCAGATATCCATTTTTGTTACGGAT
ACTTTACTAGGAGCAAGAGTTAACGCTGCTATTGAACAAAATATACCTATTGTACATTTC
AAATGGATTCTCGATTGCCAAAAAAGAAGCGCACTGTTACCGTACGATCCCTATTATCTT
TTACCAAATATTAAAGACCTGCCCTATGATTCAATCGGATCAAACTCTTGCGATTGCTGG
GATAAAATAAACACCACCTTTCCAACCAATATCGATGCCCAATCCTCTCTGCAGCGGCAG
CAATCCTCCAGTACCCTGACTCCTTCGCTCCCGAAAACATCATCCCTCTTGAATAAATTT
AAACCAAAGGGTGAAAAAATATGGGACAAGGCAATGTCTCTACAGCAGCATAGTAAGACA
AATTTTTCAGTACTAGGGCAGTCACCATTATCGATAAATAACAAACAAGAAGATTTAAGT
GATAATAGTACTTTGATTTTCAAAAATTGTGCGTTTATCATTCATCATATTTTTCCTGGC
AATCACCGTTCAATACTAACCAAAATTGTTGTTCAAAATGGGGGTAAAATTGAGACGTCT
TACTTGAGCGGCATTTACGATCATTCTTATTACATCATTCCAAGTAATAAAGCTCTTGAC
TCCTTCAATGATTTACCTGAGATTATAGATGATAATGATGGTATAGTTACAGAATTTTTC
ATTGAACGCTGCTTGTATTATCAAAAATTACTACACCCAATAGATTTATGGTCAAAACCC
TTCCTCAGCACAATAGAGTTTCAAGTTTCGTCTTCTTCAAAGTTATTGCATCATGAATTT
TCTTCTTCCCCTTTTCTGAATGTTACTATCACTGGATTCTCTGGCGTAGAGCTGTTACAT
CTGACTAAAGTATTAAATCTTCTAAAACCAATGGGCATCAATTATGTAGAATACCTCAAT
AAATCCACTGACATTCTGCTAATCAACTTAGCAGCTTTACCCAGTATCCCGAAAACCCAT
CCGTTATGGTCGAATGAATTTAGCGATCTTTTTACTCAGTTTTGCATTAATAACAATAAT
GATGATCCTGGTGATAATAACAGAAAAGATTTTCAAAATAATTCAATCTTGAGAAATTCG
ATGAAAAGGAAAATTGAATATATCAAGAAATTCCACTCCATACCGGTAGTTACTCCAGCA
TTTATTTTTAAATTATTGTCCGCTGCATCTGGAGAAAATAATGAAATCTTTTTAAACAAT
ATCAAGTGGTGTATTATCTGCCCAAGAGGACACAAGGACGATTTTAAATGTAAGATAAAA
AAACCATACTATACCAGCATTAGTTCAGAAAAAAAGTACCAAAACAATGATCCAAAAATC
GACAAAACTATTCTTTTGAAAAGAAACAATTCCTCATTATCGGAGCACTCTATGAAAGAT
ACCAAAAACGAATTATTGCAGAAAATTAGAGAAACTGATTCTGGAAGAAAAAAGCGTAGT
GTCTCATCGAGTATCATGGATGTTTCTTCAGAGAGACAAATGCCGGATACGAAAAGGATC
AAGTTGGAGTCACTGCCAAAAAATTTCGTTCCTAAACAAATTAAACGAACCACGAGTTGG
GGCACAATAATGTCAGAAAATGTGCCTACAGAGCAGCCGACTGCAATTTCTAATCCAGAA
GAGATCCCAAGAACTGAGGAAGTTTCACATACTCAAGTTACCTATGGCTCCATTCAAGAT
AAGAAACGTACTGCCTCTTTAGAAAAACCTATGAGACGACAGACAAGAAATCAGACAAAG
GAATTAGATTCTTGA Promoter Sequence
Download FASTA
>DPB11 YJL090C
CTTTCTGACAGAGAAATCAGTGATTGCGTTAGAGGAGCTTTGACCGGTTGGTACTATCAG
GACTTTATTGCTGCAGGAATCTGTATCATCGAGGGAATAAGACCTGCCATATTTCCTCTT
GGCCATCGTCTATTCAGAGTAGCGAGAAGAAAAAAAGAAGCAAAAAAAAAAAAAAAAAAC
GAGCAAAAGAAATCGAGCAAAGGAGAATGAGCAAAGGATAAACGGAAAACAATGGTAAAG
AGGATTAGCCGCTGAACTAGATTGTAAATTGAAGCGGAAAAGAAAACAAAGGAGAGGAAA
TCGGAGAGGCAGAAAGCTTTCTGCCTTATATACTTTTTTTTTTGCCGCCGAGTTCTGAGA
TCACGCCCTTAAATTTAGCCGCCAAAACACCGGTCGAACGGCGAAAATGGATCGGAGTCT
TGATTGCACCCACACCTCGCATTTTGTGCACTAACATAAAATATGACGAAGTGAGAGTCA
TGACACACAGAATAACTTAAAAATACTTGAGGAAAAAGTTCTCATATTATGAGGTCATAA
TAACTACATCGTTATTGTTGCGATATAACTTCAATGTTTTCTGCCTGCAAAAGAATCCTT
CCTTTTCCTTCTTTAATTGAAGAGTCCATGTAACCTTGTTTCGTTACTTATATTTATTCA
CCTTTCTACTTTAGTCACATAACGTAATCTGGGCATAATCATTGAGGTATCATTATTAGC
TTGAACTCGTGGTTCCTATTGTCGCCAGGTTTCTTTCAACGCATTTGCTCTTTCCGCTTC
GCATACGGCGGTGATCAAATGCAAAACTTACCCTCATCAGTATAAGAGAAGAAAAACTGC
ATGGACTATTCGCGTATTGCCTGGTAAAGCTATATAGTACTATTGGTAATGTTTGTACTG
TTTTATGTACATGATGAATAAGAAGAGACAAATTTTACGTGATATATAAGTCTTCTATTT
CTAGTATGGCAGGTATTTTATCAGTAGCATTAATATTACT
Chr coordinates
Chr X from 265051-262757
