Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name RPL8A
Systematic Name YHL033C
Alias eL8, L4A, L8A, L8e, MAK7, rp6, YL5
Strain S288c
Description Ribosomal 60S subunit protein L8A; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; L8 binds to Domain I of 25S and 5.8 S rRNAs; mutation results in decreased amounts of free 60S subunits; homologous to mammalian ribosomal protein L7A, no bacterial homolog; RPL8A has a paralog, RPL8B, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>RPL8A YHL033C
ATGGCCCCAGGTAAGAAAGTCGCTCCAGCTCCATTCGGTGCTAAGTCAACTAAGTCTAAC
AAGACTAGAAACCCATTGACTCACTCTACTCCAAAGAACTTCGGTATTGGTCAAGCTGTC
CAACCAAAGAGAAACTTGTCCAGATACGTCAAATGGCCAGAATACGTCAGAGTGCAAAGA
CAAAAGAAGATCTTGTCCATCAGATTGAAGGTTCCTCCAACCATTGCTCAATTCCAATAC
ACTTTGGACAGAAACACCGCTGCCGAAACCTTCAAGTTGTTCAACAAGTACAGACCAGAA
ACTGCTGCTGAAAAGAAGGAAAGATTGACCAAAGAAGCTGCCGCTGTTGCTGAAGGTAAG
TCCAAGCAAGATGCTTCTCCAAAGCCATACGCTGTCAAGTACGGTTTGAACCACGTTGTT
GCCTTGATCGAAAACAAGAAGGCTAAGTTGGTTTTGATTGCTAACGATGTCGACCCAATT
GAATTGGTTGTCTTTTTGCCAGCTTTGTGTAAGAAGATGGGTGTTCCATACGCCATTGTC
AAGGGTAAGGCTAGATTGGGTACCTTGGTTAACCAAAAGACCTCTGCCGTTGCCGCTTTG
ACTGAAGTCAGAGCCGAAGACGAAGCTGCTTTGGCTAAGTTGGTTTCTACCATTGACGCT
AACTTCGCTGACAAATACGATGAAGTCAAGAAGCACTGGGGTGGTGGTATCCTTGGTAAC
AAGGCTCAAGCCAAGATGGACAAGAGAGCTAAGAACTCCGACTCCGCTTAA
Promoter Sequence
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>RPL8A YHL033C
TAGTTTTCGTCCCCGCATTTAGTGGCCTATTCGCTCCCTATTGGGACCCAGATGCCAGAG
CCACCATAATGGGGATGTCTCAATTCACTACTGCCTCCCACATCGCCAGAGCTGCCGTGG
AAGGTGTTTGCTTTCAAGCCAGGGCTATCTTGAAGGCAATGAGTTCTGACGCGTTTGGTG
AAGGTTCCAAAGACAGGGACTTTTTAGAGGAAATTTCCGACGTCACATATGAAAAGTCGC
CCCTGTCGGTTCTGGCAGTGGATGGCGGGATGTCGAGGTCTAATGAAGTCATGCAAATTC
AAGCCGATATCTTAGGTCCCTGTGTCAAAGTCAGAAGGTCTCCGACAGCGGAATGTACCG
CATTGGGGGCAGCCATTGCAGCCAATATGGCTTTCAAGGATGTGAACGAGCGCCCATTAT
GGAAGGACCTACACGATGTTAAGAAATGGGTCTTTTACAATGGAATGGAGAAAAACGAAC
AAATATCACCAGAGGCTCATCCAAACCTTAAGATATTCAGAAGTGAATCCGACGATGCTG
AAAGGAGAAAGCATTGGAAGTATTGGGAAGTTGCCGTGGAAAGATCCAAAGGTTGGCTGA
AGGACATAGAAGGTGAACACGAACAGGTTCTAGAAAACTTCCAATAACAACATAAATAAT
TTCTATTAACAATGTAATTTCCATAATTTTATATTCCTCTCCACCTTCTATTGCATCATG
TACTATTCAAATGACTGTAACACTAGTATTATGAAGAAAACACCCAAACATATCTAGGCC
ATCAGATTTTTTTTTTTTCATTTTTCATTTTTTTCTCATTTTCTTATTTATTTTTATTGA
AAAATAATAACCGACGCAAACAAATTGGAAAAACCAACGCAAAAAAAAAAAGACGCTAAA
TTGTTTATAAAGGCGAGGAATTTGTATCTATCAATTACTATTCCAGTTGTCAGTTTACAT
TGCTTACCCTCTATTATCACATCAAAACAACTAATTCGAA
Chr coordinates Chr VIII from 36025-35255
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