Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name HAC1
Systematic Name YFL031W
Alias ERN4, IRE15
Strain S288c
Description Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog); regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway triggers efficient Hac1p translation; two functional forms of Hac1p are produced; translation initiation is repressed under non-stress conditions; protein abundance increases in response to DNA replication stress
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>HAC1 YFL031W
ATGGAAATGACTGATTTTGAACTAACTAGTAATTCGCAATCGAACTTGGCTATCCCTACC
AACTTCAAGTCGACTCTGCCTCCAAGGAAAAGAGCCAAGACAAAAGAGGAAAAGGAACAG
CGAAGGATCGAGCGTATTTTGAGAAACAGAAGAGCTGCTCACCAGAGCAGAGAGAAAAAA
AGACTACATCTGCAGTATCTCGAGAGAAAATGTTCTCTTTTGGAAAATTTACTGAACAGC
GTCAACCTTGAAAAACTGGCTGACCACGAAGACGCGTTGACTTGCAGCCACGACGCTTTT
GTTGCTTCTCTTGACGAGTACAGGGATTTCCAGAGCACGAGGGGCGCTTCACTGGACACC
AGGGCCAGTTCGCACTCGTCGTCTGATACGTTCACACCTTCACCTCTGAACTGTACAATG
GAGCCTGCGACTTTGTCGCCCAAGAGTATGCGCGATTCCGCGTCGGACCAAGAGACTTCA
TGGGAGCTGCAGATGTTTAAGACGGAAAATGTACCAGAGTCGACGACGCTACCTGCCGTA
GACAACAACAATTTGTTTGATGCGGTGGCCTCGCCGTTGGCAGACCCACTCTGCGACGAT
ATAGCGGGAAACAGTCTACCCTTTGACAATTCAATTGATCTTGACAATTGGCGTAATCCA
GAAGCGCAGTCAGGTTTGAATTCATTTGAATTGAATGATTTCTTCATCACTTCATGA
Promoter Sequence
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>HAC1 YFL031W
AGAGCCACTATCATCGGCGACTCCTGTGATCGTGTTCCACTGTGGAGAGCCATATCGCAC
CTTGCCGTCCAGTTCCAGCTCCAAGATCATACACGGATTCTTCTCTGTGGCCAGCTGCAG
ATATTTTTCATAATTGGAGGAAGTCAATGAGCTTGGGTTCGAATTCGATGATATCGGGGA
GAGCTTGTTTATGCCAAGTCCCTCTTTCATAGCCTGAGATCCGCCTGCGGTGTTACTTCT
ATTGAACATCTGTCTTCCTCTACTGGGCTTATCTATTCTATCAAATGAGGCAAGAGAAAG
GAAAGGGAAAAAAAAAAAGGGAAAATGCTTGATGAGTTAGGAATTCAGTAAAAGCACCCA
CCAGAACCTCTACAGCAGGCCTTCCAGGAGTGGTTAAGAGGATAGAGAATTCTGTATATA
TATATACGTCTATATCTATACAAAAAACGGCAGACAATGCAGAAGTTGAAAATGCTGTGA
TACGAACAACAACTTATTTTTACAATGAAAAACAACACCAAGCTGCCAAAAGCTGTATAT
TAAAGTTAAAGCTCCCTCATTTTTAGTAAGGACGCTTTCTTTTCCCACAAAAGGGACGAG
GAAAAAAAGAAAAACCTGGAAATATAGTCACGTGACATGAATAAACAAGACCTAGGGCAA
TATGGAAAAAGAAGCTAGGATAAAAATACATTTATGAGGGTTGTAAGGCAAAGTGGCTCA
GCATTAAGTAGGGCTAAAAAGAGTCGCAAATATACATCGTACCGAGTGATGAACGTGGTT
TTGAACACCTTGTTCTCTTTTGTTCTCGCTCCCTACATTCACTATATATTAGAAGAAATT
TCACCTCAATGGACAACTCGAGAAATGAATACAGAAATATGTTTTTTAGCGAAATTTTCC
TTTCTTCTTGTCTTCTTGTTTTATTTAAACTTCCAAGGCTTTAACTCAGTGTCAAACATA
ACAACCTCCTCCTCCCCCACCTACGACAACAACCGCCACT
Chr coordinates Chr VI from 75179-75839,76092-76147
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