Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
VMS1
Systematic Name
YDR049W
Strain
S288c
Description
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, component of a Cdc48p-complex; involved in protein quality control; exhibits cytosolic and ER-membrane localization; contributes to ER-associated degradation (ERAD) of specific substrates at a step after their ubiquitination; translocates to mitochondria under oxidative stress and forms a complex with Cdc48p and Npl4p that is required for ubiquitin-mediated mitochondria-associated protein degradation (MAD)
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>VMS1 YDR049W
ATGAATTCACAAAAGGCGAGTAAAATGACTGGCTCACTAAAAAAGAATGATCTTTATATT
TTTGATTTGTCTGAGCAACTTCTGAATTCATTGAAATTGATGAGCTTTGACTCCACACTG
CGAGAAGTTGAAGTAGAGAAGACATCTGATAATGATAGAAACAAGGAGTCTGGAGATCTC
CAAATAGCAAGAAAGAAGGTCACATCAAATGTTATGCGTTGTAGTGTTTGTCAAATGAGC
TTTGATTCCAGAAATGAACAAAAGGCCCACTACCAGACTGATTATCATTTGATGAATGTT
AAGCGTAACCTTAGGGGGCTGGATATCCTATCCGTTGAGGAATTCGATGCGCTGATTTCT
AAGGAGCATGGTATCAAGTCTGAAGACGAAAATTCTGGCGGCGAGCAAACTTCAAGCGAT
CACGAAGAAAGTGAGGAAGCCAGCGATCGGGACCCGGACCTACAAACTAATAATTATATG
GAAACTATAATCGAAAATGATTTGCAGAAATTAGGGTTCCAAAAAGACGAGTCGGATGCT
ATTAGCCATATTAATACCCAATCGCCCTACATTTATTTCAAATCGAAGTATCTTCAAAAG
AATGAGGTCTTGGCGATTTATAAGTCTCTATTTAATAAAAGGAGTCTTTCCAACCCCAAT
GAAGCTTTGACTTTTTGGAATTCGCAAGAGAACCCAATGGCCATTTCAGCTCTGTTTATG
GTGGGAGGTGGACATTTTGCGGGAGCAATTGTTTCTCATCAAAGACTCAATGTCAAGGGG
AACGCGCACAAGAAGGACGAAACCTTAATTGAGCAAGCGGTCAATTTCTTAGAGCACAAG
ACGTTTCACAGGTATACTACCAGAAGGAAGCAAGGTGGTTCTCAGTCAGCAATGGACAAT
GCAAAGGGAAAAGCTAACTCTGCCGGTTCAGCACTTCGTAGGTACAATGAAAGCGCTTTA
AAAACAGATATACAGGGTGTGTTGAAGGACTGGGAACCTTATCTGTCAAAGTGTGATAAT
ATTTTTATTCGAGCTCGCAATGTCAGTGATAAAAAAATTTTTACTGATAATACCGTTCTG
AACAAGGGTGATGAAAGGATAAAGAGCTTCCCTTTTACCACGAACAGGCCCACTGTATTA
GAATTGAAGAAGGCATGGTGCGAACTTTCCTACCTGAAAATATTACCTAAGCCTGAACCA
TTGGCAGTGAAAGAAACAGTACAAAAGTTAGAAGTGTCGAACAAAAAGGACGAATTTAAA
GAAAAACAAGAACCGTTACTGGAAGAAATCCAAACAGAAGAAATAATTTCTCTGCTGAAG
AAAGGAAGGGCACCGTTATTGATATCCTTCTTAAAAAAGAATAAGCTTGATGGAAACTTT
CGGTTAAAGCCTGAGAGTAAATATTCCTTAACCCCTACCATGTTACATTATGCATCGCAG
CAAGGGATGAAACAGATGGCACTGATTTTGCTCTCAAATATTAAATGCGATCCAACGATC
AAGAACAGACTAGGAAGGACTGCGTGGGATTTGAATAGAAACGACGACGTGAGACACGCG
TTTCAAATTGCAAGATACAATCTTGGAGAGTCTTTCACTAATTGGGACGAAACTCATATC
GGTCAGCCATTGAGCAGAGAACAAGTTGATGAAATCAATGAAAAGAAAAAAGCAATAGAG
AATGAAAAGGCAGAAAAACTGATTAAATTGGAATTAGAAGCCGCCAAGGAAAAACAAAGA
TTTGCTAAAGATGCAGAGAGGGGTCCAGGCAAAAAGTTAACCAATATTCCTTCAATTCAG
CAACAAAATTTGAATTCTTTGACCGATGAACAGAGACGCAGATTGATGAGAGAACAAAGG
GCTAGAGCCGCAGAAGAAAGGATGAAAAAGAAATACTGA
Promoter Sequence
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>VMS1 YDR049W
AGGCAATCACCATGACAAGGATCAAGTTGGATGGTGAGGTTCCCTTATTTGGCTTTTGCG
GGGGACCTTGGACTCTAATGGTTTATATGACGGAAGGCGGTGGATCCCGTCTTTTCAGAT
TTGCCAAACAATGGATTAACATGTATCCAGAGCTTTCTCACAAATTATTACAAAAAATCA
CTGATGTGGCCGTGGAGTTTCTGAGTCAGCAAGTCGTGGCGGGTGCTCAAATACTACAAG
TTTTTGAAAGTTGGGGTGGTGAGCTTTCGTCTGTAGATTTTGATGAGTTTTCCCTACCAT
ATTTAAGACAAATTGCCGAAAGAGTGCCTAAAAGATTGCAAGAATTAGGTATCATGGAAC
AGATTCCTATGATCGTTTTTGCGAAAGGGTCGTGGTATGCTTTGGACAAGCTATGCTGTT
CAGGATTTGACGTTGTTTCGTTGGACTGGTCCTGGGACCCAAGAGAAGCGGTAAAAATAA
ACAAGAACCGTGTCACCTTGCAGGGCAACCTGGATCCTGGCGTCATGTATGGTTCTAAAG
AGGTAATAACAAAGAAAGTTAAACAGATGATTGAGGCTTTTGGAGGTGGGAAGTCCCGCT
ACATTGTTAATTTCGGTCACGGTACCCACCCTTTCATGGATCCAGACGTCATCAAGTTTT
TCTTGGAGGAGTGCCACAGAATTGGTTCGAAGTAATGTGGAAATATTGATTCTTATAGTG
TTATAAGTGATAATATACGTTTATGTAAATAATATCTTTTTCACAACGTTCAAAAGTGGC
CTTTTTTCTTTTTTCGATATTCTGTATATTTATTACGATTTTTTTTTTTTTCAGATATTT
ATTTTTGCAGGTTCTCTGAATGGATGTAGTGACAAAATCTTAAATAGAAGAAAATAAAAG
ATGAAGGTATATGAAAATAAATGAGAATGCATATCACCTTTCCTTCGAAGAAAAAGGATT
TTCAAAAGATCTGCACGCCTGTTGACAAGCTTCCAATAGC
Chr coordinates
Chr IV from 553254-555152