Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Protein Information

Protein Name Cbf1p
Description Basic helix-loop-helix (bHLH) protein; forms homodimer to bind E-box consensus sequence CACGTG present at MET gene promoters and centromere DNA element I (CDEI); affects nucleosome positioning at this motif; associates with other transcription factors such as Met4p and Isw1p to mediate transcriptional activation or repression; associates with kinetochore proteins, required for chromosome segregation; protein abundance increases in response to DNA replication stress
Aminoacid Sequence
Download FASTA
>CBF1 YJR060W
MNSLANNNKLSTEDEEIHSARKRGYNEEQNYSEARKKQRDQGLLSQESNDGNIDSALLSE
GATLKGTQSQYESGLTSNKDEKGSDDEDASVAEAAVAATVNYTDLIQGQEDSSDAHTSNQ
TNANGEHKDSLNGERAITPSNEGVKPNTSLEGMTSSPMESTQQSKNDMLIPLAEHDRGPE
HQQDDEDNDDADIDLKKDISMQPGRRGRKPTTLATTDEWKKQRKDSHKEVERRRRENINT
AINVLSDLLPVRESSKAAILACAAEYIQKLKETDEANIEKWTLQKLLSEQNASQLASANE
KLQEELGNAYKEIEYMKRVLRKEGIEYEDMHTHKKQENERKSTRSDNPHEA* 
Transcription Factor
Binding site(s)
CACGTG
RTCACGTG
RTCACRTG
TCACGTT
VCACGtg
gaxcxgtCACGTGactxxtcg
DxcxgatCACGTGaYxDgxxxa
CACGTGAYc
gCACGTGa
CACGTGAcc
axCAcgtg
CAcgtga
AAAGCACGTG
AAAGCACGTGAACA
AAAGCACGTGAG
AAAGCACGTGCNCA
AAAGCACGTGGNC
AAANCACGTG
AAATCACGT
AAATCACGTGACA
AAATCACGTGCGA
AAATCACGTGGT
AAATCACGTGT
AAATCACGTTT
AACCACGTG
AACCACGTGTAT
AAGCACGT
AAGTCACGTGAAA
AAGTCACGTGCAA
AAGTCACGTGCAC
AAGTCACGTGG
AAGTCACGTGTT
AANCACGTG
AATCACGTGGGA
AATCACGTGTG
ACATCACGTGAAA
ACATCACGTGAAT
ACATCACGTGATA
ACATCACGTGCACA
AGAGCACGTGCGA
AGATCACG
AGATCACGTGAAT
AGATCACGTGCAA
AGATCACGTGCACA
AGATCACGTGGAG
AGCACNTGC
AGGCACGTGAT
AGGCACGTGCTA
AGGTCACGTGAAG
AGGTCACGTGANC
AGGTCACGTGC
AGGTCACGTGTTT
AGGTCACGTT
AGTCACGTGANA
AGTCANGTGA
AGTCANGTGAT
ANGCACGTG
ANGCACGTGC
ANTCACGTGATC
ATATCACGTGAAT
ATATCACGTGATT
ATATCACGTGCTT
ATATCACGTGGA
ATCACATGAC
ATCACATGATA
ATGGCACGTGTAT
ATGTCACGTGCAC
ATGTCACGTGCACA
ATGTCACGTGCTT
ATGTCACGTTTT
ATNTCACGTGG
CACGTGAAA
CACGTGAAT
CACGTGAG
CACGTGGAA
CAGCACGTG
CAGCACGTGGG
CAGTCACGTGANA
CAGTCACGTGTAT
CANCACGTG
CANCACGTGAG
CANTCACGTGATC
CCATCACGTGATA
CCATCACGTGTA
CCGTCACGTGGAA
CGATCACGTGAAT
CGATCACGTGGAA
CGATCACGTGGTC
CGGCACGTGAT
CGTCACGTGCAC
CGTCACGTGGGA
CGTCACGTGTAA
CNTCACGTGCNA
CTATCACGTGATA
CTATCACGTGCCA
CTATCACGTGT
CTATCACGTGTG
CTATCACGTGTTT
GAAGCACGTG
GAGCACGTGA
GANCACGTGA
GATCACATG
GATCACGTGATC
GATCACGTGCTA
GATCACGTGGG
GATCANGTGA
GATCANGTGAT
GCACGTGAAC
GCACGTGCNC
GCAGCACGTG
GCATCACGTGAAA
GCATCACGTGACT
GGCACGTGAT
GGCCACGTGA
GGGTCACGTGAT
GGGTCACGTGCAT
GGGTCACGTGCGG
GGGTCACGTGGGA
GGGTCACGTGTAT
GGGTCACGTGTGT
GGTCACATGGT
GGTCACGTGANT
GGTCACGTGCGG
GGTCACGTGCTCA
GGTCACGTGTAA
GGTCANGTGA
GGTCANGTGAT
GNTCACGTGCTC
GTCANGTGA
GTCANGTGAT
GTGTCACGTGAG
GTGTCACGTGANA
GTGTCACGTGATA
GTGTCACGTGATC
TAAGCACGTGCNCA
TAAGCACGTGCNG
TAATCACGTGACT
TAATCACGTGATC
TAATCACGTGCG
TAGCACGTG
TAGTCACGTGANA
TAGTCACGTGCG
TAGTCACGTGCTC
TAGTCACGTGGG
TAGTCACGTGGT
TAGTCACGTGGTC
TATATCACGTGATC
TATATCACGTGCTCA
TATCACGTGCAA
TATCACGTTTT
TATCANGTG
TCACGTGANC
TCACGTGATA
TCACGTGATC
TCACGTGATT
TCACGTGCTCA
TCATCACGTGGA
TGATCACGTGAAA
TGATCACGTGATA
TGATCACGTGATT
TGATCACGTGCGA
TGATCACGTT
TGCCACGTGA
TGGCACGTGA
TGGCACGTGCNA
TGGTCACGTGAAT
TGGTCACGTGCAA
TGGTCACGTGCAT
TGGTCACGTGCG
TGGTCACGTGCGG
TGGTCACGTGG
TGGTCACGTGGA
TGGTCACGTGGTC
TGGTCACGTGGTT
TGGTCACGTGTG
TGNTCACGTGA
TGTCACATGAC
TGTCACGTGCAA
TTATCACGTGACT
TTATCACGTGAT
TTATCACGTGATC
TTATCACGTGTG
TTCATCACGTGCG
TTCATCACGTGTGT
TTGATCACGTGAAA
TTGATCACGTGACA
TTGATCACGTGATT
TTNTCACGTGAT
AAACCACGTGAAAA
AAACCACGTGAG
AAAGCACGTGTG
AAANCACGTGTA
AAGTCACGTT
AAGTCACGTTT
AATCACGTTTT
ACATCACGTGTG
ACATCACGTGTGT
ACATCACGTT
ACATCACGTTT
AGATCACGTTT
AGCCACGTGTA
AGGCACGTGCTGC
AGGCACGTGGA
AGGCACGTGGT
AGGCACGTGTAT
AGGCACGTGTG
AGTCACGTTT
AGTCANGTG
ANCACGTGC
ANCACGTGCNC
ANGCACGTGAACA
ANGCACGTGGT
ANTCACGTGCAA
ANTCACGTGCTC
ATCACATG
ATCACATGA
ATCACATGGT
ATGGCACGTGAG
ATGGCACGTGCGA
ATGGCACGTGTG
ATNTCACGTGAAT
ATNTCACGTGAT
CACATGAC
CACATGAT
CACGTGAACA
CACGTGAAG
CACGTGCAA
CACGTGCGA
CACGTGCGG
CACGTGCTGC
CACGTGGAG
CACGTGGGA
CACGTGGNC
CACGTGGT
CACGTGTT
CACGTGTTT
CAGCACGTGC
CAGCACGTGTTT
CAGTCACGTT
CANTCACGTGTAA
CCATCACGTGGA
CCATCACGTGTT
CCGTCACGTGAAG
CCGTCACGTGG
CGATCACGTGTG
CGGCACGTGAG
CGTCACGTTTT
CNTCACGTGCTG
GAGCACGTGGT
GANCACGTGGTC
GATCACATGA
GATCACGTTTT
GCACGTGCAC
GCACGTGCG
GCACGTGGAA
GCAGCACGTGGG
GCCACGTGTTT
GGCACGTGAAT
GGCCACGTGCAG
GGGTCACGTTT
GGTCACATG
GGTCACATGATA
GGTCANGTG
GNTCACGTGGTT
GTCACATG
GTCACATGATA
TAGTCACGTTT
TAGTCACGTTTT
TATATCACGTT
TATCACATG
TATCACGTGGAA
TATCACGTT
TATCANGTGNT
TCACATGA
TCACATGAC
TCACGTGC
TCACGTGCTA
TCACGTGGAG
TCATCACGTGT
TGAGCACGT
TGATCACG
TGATCACGTTT
TGCCACGTGAAA
TGCCACGTGC
TGCCACGTGCGA
TGGCACGTGGG
TGNGCACGTGGT
TGTCACATG
TGTCACATGAT
TGTCACGTTT
TNTCACGTGAG
TTATCACGT
TTCATCACGTGTAA
TTGATCACGTGGG
TTGATCACGTT
TTGATCACGTTT
TTNTCACGTGATA
TTNTCACGTGCTA
AAAGCACGT
AAANCACGTGCAG
AACCACGTGTT
AAGCACGTGTA
AATCACGT
ACATCACGTGGAA
AGGCACGTGTTT
AGGTCACGTTTT
AGTCACGT
AGTCACGTTTT
ATGTCACGT
ATNTCACGTGTA
CACGTGCAG
CACGTGTAT
CANCACGTGCAT
CANCACGTGCNA
CANTCACGTGCTTA
CTATCACGTT
GANCACGTGAACA
GANCACGTGAAT
GATCACATGGT
GATCACGTT
GCACGTGAAAA
GCACGTGTTTC
GCAGCACGT
GCATCACGTT
GGCACGTGG
TAGCACGTGC
TATCACATGAT
TCATCACGTGTA
TGCCACGTGGG
TTATCACG
TTATCACGTTT
TTNTCACGTGC
Regulon See Venn diagram regulon   
Documented targets See documented regulated genes
Potential targets See potential regulated genes (Attention! Can return hundreds of genes)
External source Open in SGD external link
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