Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
NDI1 Systematic Name
YML120C Strain
S288c Description
NADH:ubiquinone oxidoreductase; transfers electrons from NADH to ubiquinone in respiratory chain but does not pump protons, in contrast to higher eukaryotic multisubunit respiratory complex I; upon apoptotic stress, is activated in mitochondria by N-terminal cleavage, then translocates to cytoplasm to induce apoptosis; homolog of human AIFM2; yeast NDI1 complements several phenotypes of human cell line with mutated MT-ND4, implicated in Leber hereditary optic neuropathy External sources
Open in SGD
Open in KEGG
Gene Sequence
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>NDI1 YML120C
ATGCTATCGAAGAATTTGTATAGTAACAAGAGGTTGCTCACCTCGACGAATACGCTAGTC
AGATTCGCTTCCACCAGATCCACAGGGGTGGAAAACTCCGGAGCAGGTCCTACATCTTTT
AAGACCATGAAAGTCATTGACCCTCAGCACAGCGACAAACCAAACGTGCTGATACTGGGT
TCGGGGTGGGGAGCTATTTCGTTTTTAAAGCACATTGACACCAAGAAGTACAACGTTTCC
ATCATCTCTCCTAGAAGCTATTTCTTATTTACGCCTTTGTTACCTTCTGCACCAGTTGGG
ACAGTAGACGAAAAGTCAATTATTGAGCCCATCGTTAATTTTGCTCTCAAGAAAAAGGGG
AACGTTACCTACTATGAGGCAGAAGCCACCTCTATCAATCCCGACAGGAATACCGTTACC
ATAAAATCATTATCTGCCGTTAGCCAGCTATACCAACCTGAAAACCATCTAGGGCTGCAT
CAAGCAGAACCTGCTGAAATTAAGTACGATTATTTAATCAGTGCTGTAGGTGCGGAACCT
AACACATTTGGTATTCCTGGGGTCACTGATTACGGTCATTTCCTGAAGGAAATTCCCAAC
TCTTTGGAAATAAGAAGAACTTTTGCCGCCAATCTAGAGAAGGCTAACTTATTGCCAAAG
GGTGATCCCGAAAGAAGAAGACTACTGTCCATTGTCGTGGTTGGTGGTGGGCCTACTGGT
GTAGAGGCCGCTGGTGAACTACAGGATTATGTTCACCAGGACCTGAGAAAGTTTCTCCCT
GCATTGGCCGAAGAAGTCCAAATTCACTTGGTCGAAGCTCTGCCCATCGTTTTGAATATG
TTTGAGAAAAAGCTTTCATCATACGCGCAATCACATTTAGAAAACACTTCGATCAAAGTA
CATCTGAGAACGGCTGTCGCCAAAGTTGAAGAAAAGCAATTGTTGGCAAAGACCAAACAC
GAAGACGGTAAAATAACCGAAGAAACTATTCCATACGGTACTTTGATTTGGGCCACGGGT
AACAAGGCAAGACCGGTAATCACTGACCTTTTCAAGAAAATTCCTGAGCAAAACTCGTCC
AAGAGAGGATTGGCAGTGAATGACTTTTTGCAGGTGAAAGGCAGCAACAACATTTTCGCC
ATTGGTGACAATGCATTTGCTGGGTTGCCACCAACCGCCCAAGTAGCGCACCAAGAGGCC
GAATATTTGGCCAAGAATTTTGATAAAATGGCTCAAATACCAAATTTCCAAAAGAATCTA
TCTTCAAGAAAGGATAAAATTGATCTCTTGTTCGAGGAGAACAACTTTAAACCTTTCAAA
TACAACGATTTAGGTGCCTTAGCATACCTGGGATCCGAAAGGGCCATTGCAACCATACGT
TCCGGTAAGAGAACATTTTACACCGGTGGTGGCTTAATGACCTTCTACTTATGGAGAATT
TTGTACTTGTCCATGATTCTATCTGCAAGATCGAGATTAAAGGTCTTTTTCGACTGGATT
AAATTAGCATTTTTCAAAAGAGACTTTTTTAAAGGATTATAG Promoter Sequence
Download FASTA
>NDI1 YML120C
AGGTTTTTTGTGGGTGACTCTGGATAATAGAAAAACTGCTGGTTGGAATCGAAAGTCGCT
TTTTGTTGGAAGCTCAGGACTGGCTGCTGATTCAAATTAAACTGCGTAGGAGGCAGGACC
AGCCCACCGCTGTTATTGATGTAAGATGATTTGTTATTGAGCGTCCTTCTTGGCGACACT
GATGGACTTGGGCTCATTGCTACCTACTTTTTTTCTTACTGACCTAAGGCTGCAGGTGCA
AGAAAAGAGTAAAAGAATGTTAAAATACGTTTTGAAAGGTCTCTGTTTTCATGTACAATT
GAGGGATAAAAAAATCTTTTCTTTCTTTCAATGCGGATGATTGACACTTTCTTATTTTGT
GTTTTTATTTATGTTCTTTCCTAATCTGGAAAGCATATTAAAGACCGGCGCTACCCGGTT
AAGTAATCATACACGTGAAAAGCACGTGAACAACAAAGCACTTTAAAACTCATATACTAC
GCATTTAAAGAATGCTAAAACGGCAATTGCCACTGGGCACCATTTAAAAGGTCAATAATG
AATCTGTGACCTTTCTTTGCTATAGCATCACTACAACTATGTGTTGCTTGTCGCTAGCAA
CGAACCTATTATTCCTTCGCTTTATTGTCGAAGACCACAAAATACTCCAAAGCAATAGAA
TGTCTCTTTCCGCAAATAACTTACTCAGGGAAACAATACGAATATGTGCAGATTGCCGAT
CATTGCTGAAATGCCTCAAAAATATGCATTTTCTCATGACCTATTCATTCGGACCAATCA
TATGAAGGCATTGAACGTCCGGGTAACCACAATAAGAGTGCTCCCCCTTAGCGCTCTTGG
TTATTGCCGGTATTTGCAACGTCGACAGGGTATATATAAGATGTATAGGGCATAGTGGGG
AAGGAGTTTTAACTACCAATTGAGGAGTTTCAGGTAGGGTGTCAGTTTCATCACATCATC
GAATTACACGTTTACCCAAGAGAAGAAACTAAAAACCACT
Chr coordinates
Chr XIII from 29807-28266
