Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
YAE1 Systematic Name
YJR067C Strain
S288c Description
Substrate-specific adaptor protein involved in apo-Rli1p maturation; subunit of the Yae1-Lto1 complex, recruiting apo-Rli1p to the CIA targeting complex, facilitating the insertion of an Fe/S cluster by the Fe-S biosynthetic machinery; deca-GX3 motif crucial for complex formation; essential for aerobic but not anaerobic growth; homolog of human YAE1D1, which is overexpressed in oral cancers; co-expression of YAE1D1 and LTO1 homolog ORAOV1 restores growth and Rli1p maturation after YAE1 depletion External sources
Open in SGD
Open in KEGG
Gene Sequence
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>YAE1 YJR067C
ATGTCGAATACTTGGGACGATGTATGGGCATCAGACAGTGATGTCGAAACTGAACGATCT
CCAGATTTAGTGAAGTTAAGAGAGAATCATAGCAAGAGGGGGTACTTGGACGGAATAGTG
AGTTCTAAAGAAGAAAAGCTGCAAGAGGGTTTCAATGATGGTTTCCCAACGGGCGCTAAA
TTAGGGAAACAAGTTGGCATAATTATGGGGATTTTACTTGGCCTACGAACACGTTTTGGT
GATGAAGATGAGGACCTCAGTAAGGCATATATTGATGCTCAAAAAGAATTACGCATTAAC
AAAGTACTTAGTAAGTCCATATTTGATCCAAACTTTGACTTGCAAGAAAAACATCCGCTC
ATAACAAAATGGACTGATATTGCCAATACCTATTGTGAAAAGTACCATGTGCCATCTATC
CAATAA Promoter Sequence
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>YAE1 YJR067C
GAATGTCATGAGGTACCACACCAGCTAATTCTTCCACTTGGGTAGAAGTTATGTTTTTAC
CATCACCCAAGTATTGCGCCCCCTTGGAAGCGGATTGTAATAATGTAATGCCTCTTCTCA
AGTCACCTGCCGAAATGTCCAAGATCCTTTCCAAAACTCCATCATCACATTTAACATTTT
CTTGTTCGCTGATAAACCTCAAACGGTCAATGGCATTACTTGCGTCTAGGGCTTTGAATC
TAAATTTGGAACAACGGGACGCTAGCGGGTCAATAATTCTTGTCACATAATTACAAATCA
AACAGAATCTTGTTACTCCTGAATAGGTTTCCATTGTTCTACGTAATGCACTCTGTGCAT
CGGCAGTCATTGAATCGGCCTCATCGAGAATAATGATCTTATACGGTGGGCACGGATAGT
TCTCCAAGTCATGTTTGCTAGGCTTGGATACAGTCAATCTTGCAAAATTTTTTACCTTTT
CTCTTACAATAGAGATACCACGTTCGTCAGAAGCGTTCAACTCCAATATTCTTGATTTCA
TCAAGTCGGGTCCATATAATTCTTTTGTTAGCGCTAAAATGGTAGACGTTTTACCAGTTC
CTGGGGGACCATAAAACAACATATGTGGTAGATTAGCTGACTTTAAGGTTTTCTTCAAAA
CAGTAACGGCATGATCTTGAGCTGTCACTTCATCTAGGTTTTTGGGCCTGTATTTCTCAA
CCCAGGGTTGTTGTGCCAATGATTGCTCTGCGGCTAACTTTGATATCTTACGCTTTTTAT
TTGGACCAAACCCTTCAAACATCTCAAGTGATTGCCAATACTTTCCCCCAGTATTTCTCG
CTGTCTCTCTATTTTACTTCTCTTATAGCATTGACTTGTTCGCTTGAGTTACTTCCTGAT
TGCTTTGAAATACGCGAAGTAAAAGAGTGAAAAATAACGATGAGAAAGGTTTTTGATAGA
AGAGAACAAAAAAGGAACAGTGTTACAATAGTATATAGAG
Chr coordinates
Chr X from 567444-567019
