Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
ERG11 Systematic Name
YHR007C Alias
CYP51 Strain
S288c Description
Lanosterol 14-alpha-demethylase; catalyzes C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in ergosterol biosynthesis pathway; transcriptionally down-regulated when ergosterol is in excess; member of cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p; human CYP51A1 functionally complements the lethality of the erg11 null mutation External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ERG11 YHR007C
ATGTCTGCTACCAAGTCAATCGTTGGAGAGGCATTGGAATACGTAAACATTGGTTTAAGT
CATTTCTTGGCTTTACCATTGGCCCAAAGAATCTCTTTGATCATAATAATTCCTTTCATT
TACAATATTGTATGGCAATTACTATATTCTTTGAGAAAGGACCGTCCACCTCTAGTGTTT
TACTGGATTCCATGGGTCGGTAGTGCTGTTGTGTACGGTATGAAGCCATACGAGTTTTTC
GAAGAATGTCAAAAGAAATACGGTGATATTTTTTCATTCGTTTTGTTAGGAAGAGTCATG
ACTGTGTATTTAGGACCAAAGGGTCACGAATTTGTCTTCAACGCTAAGTTGGCAGATGTT
TCAGCAGAAGCTGCTTACGCTCATTTGACTACTCCAGTTTTCGGTAAAGGTGTTATTTAC
GATTGTCCAAATTCTAGATTGATGGAGCAAAAGAAGTTTGTTAAGGGTGCTCTAACCAAA
GAAGCCTTCAAGAGCTACGTTCCATTGATTGCTGAAGAAGTGTACAAGTACTTCAGAGAC
TCCAAAAACTTCCGTTTGAATGAAAGAACTACTGGTACTATTGACGTGATGGTTACTCAA
CCTGAAATGACTATTTTCACCGCTTCAAGATCATTATTGGGTAAGGAAATGAGAGCAAAA
TTGGATACCGATTTTGCTTACTTGTACAGTGATTTGGATAAGGGTTTCACTCCAATCAAC
TTCGTCTTCCCTAACTTACCATTGGAACACTATAGAAAGAGAGATCACGCTCAAAAGGCT
ATCTCCGGTACTTACATGTCTTTGATTAAGGAAAGAAGAAAGAACAACGACATTCAAGAC
AGAGATTTGATCGATTCCTTGATGAAGAACTCTACCTACAAGGATGGTGTGAAGATGACT
GATCAAGAAATCGCTAACTTGTTAATTGGTGTCTTAATGGGTGGTCAACATACTTCTGCT
GCCACTTCTGCTTGGATTTTGTTGCACTTGGCTGAAAGACCAGATGTCCAACAAGAATTG
TACGAAGAACAAATGCGTGTTTTGGATGGTGGTAAGAAGGAATTGACCTACGATTTATTA
CAAGAAATGCCATTGTTGAACCAAACTATTAAGGAAACTCTAAGAATGCACCATCCATTG
CACTCTTTGTTCCGTAAGGTTATGAAAGATATGCACGTTCCAAACACTTCTTATGTCATC
CCAGCAGGTTATCACGTTTTGGTTTCTCCAGGTTACACTCATTTAAGAGACGAATACTTC
CCTAATGCTCACCAATTCAACATTCACCGTTGGAACAAAGATTCTGCCTCCTCTTATTCC
GTCGGTGAAGAAGTCGATTACGGTTTCGGTGCCATTTCTAAGGGTGTCAGCTCTCCATAC
TTACCTTTCGGTGGTGGTAGACACAGATGTATCGGTGAACACTTTGCTTACTGTCAGCTA
GGTGTTCTAATGTCCATTTTTATCAGAACATTAAAATGGCATTACCCAGAGGGTAAGACC
GTTCCACCTCCTGACTTTACATCTATGGTTACTCTTCCAACCGGTCCAGCCAAGATCATC
TGGGAAAAGAGAAATCCAGAACAAAAGATCTAA Promoter Sequence
Download FASTA
>ERG11 YHR007C
CTTGTTCTCTCTCGCTTCCTACGTTACTCGCGCCTGTGCACTACATTCCCACCAGATTAA
CTCACCACCAGGCAGAGAACCAATTGTTCTTGTTATTGTTCCAACCGATAATTGTAAAGC
CATTAAGGTCGTAAACGACTGCTTACTCAGGGAGATCTCCGAAAACGGCAATTGCTGTGC
ACCGTGCGACGTTATGATCGCCGCCTGTCCCGTACAGACGAACAATTGCAACAATGGGCG
GTTGTTTAGAGAGGTTTTGTGCCGCGCCCGGGAATTACCGGGGGCACAGCAAAATACGAA
ATTTCCGGCAAAATGTCTCTGTACGAAAATGAGGCCAGCCTTTATTCCCGACTAAGCCGT
ACGATTATAGTAATGTCACACGAAGTGGATACTATACGAGCAGCGCACATACAATGTGCG
TGCAAGATTTGCCGGGTTGGACAATCTTAAAGGCCGATAATCCACGAAAAACGAGACAAA
CGAAGCGCTGGCCCTAAACGAAACGAAACGAAACTAAGATTTCAAGATAATCGCTTTTCA
GATGACAATAGTCTCTTGCAGAACACAATAAGTGTGGTAGGTATCTTGCAGGAGACATCG
ATTTTATGCCTGAATTTTTTTTTTTTCTTGGTATGAGCACATCCTATTGTGCATCTCCAC
GAGTTAACGACGTTTACGTACTCGCATGTATTCGAAAAGCCTCTAAAAATTGCCCTCCAT
GTGTATTCATTATATAAGATAGCGTATTTTCCCTTAGTTTTCTTATTCCCTCTTAATTCT
CTCTTTCAATGTCTTTTTTTTTTTCCCTTTTCCTTTTTCCCTTTTCGTTATTGGTAAATT
ATTTATAAAAAGATTGATAAGCAGTATCGTTCAGCGTGTGTATTTTCGATAGGAAGTAAT
AATTTTTCATTATATTAATTAATAGTTTCCAGAAAAAATTTTTTTTCCTTCACAATTGCA
GCAGGCTTGAATAGAAACAGAACAAACGAGTAATACAAGG
Chr coordinates
Chr VIII from 121683-120091
