Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SAE2 Systematic Name
YGL175C Alias
COM1 Strain
S288c Description
Endonuclease required for telomere elongation; required for telomeric 5' C-rich strand resection; involved in ds-break repair and processing hairpin DNA structures with the MRX complex; function requires sumoylation and phosphorylation; exists as inactive oligomers that are transiently released into smaller active units by phosphorylation; DNA damage triggers Sae2p removal, so active Sae2p is present only transiently; sequence and functional similarity with human CtIP/RBBP8 External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>SAE2 YGL175C
ATGGTGACTGGTGAAGAAAATGTGTATCTAAAGTCAAGCTTATCCATTCTCAAGGAGCTC
AGTCTCGATGAACTACTAAATGTGCAGTATGACGTGACTACCTTAATCGCGAAACGTGTT
CAAGCACTGCAAAATCGGAATAAATGTGTTCTCGAAGAACCTAACAGTAAACTGGCTGAA
ATTCTATGTCACGAAAAAAATGCTCCTCAACAATCCTCTCAGACGTCTGCGGGGCCAGGT
GAGCAAGATTCTGAAGATTTCATCCTTACTCAGTTTGATGAGGACATAAAGAAAGAATCA
GCAGAGGTTCACTATCGTAATGAAAATAAACACACTGTGCAGTTACCGCTGGTTACTATG
CCACCTAATAGGCATAAACGGAAAATTTCGGAGTTTAGTTCGCCTTTAAATGGCCTCAAC
AACTTAAGCGATTTGGAAGATTGCTCTGATACTGTAATCCACGAAAAAGATAATGATAAA
GAGAACAAAACAAGAAAACTATTGGGAATAGAGCTCGAGAACCCTGAATCTACATCGCCA
AATTTATACAAAAATGTTAAGGATAATTTCCTGTTTGACTTCAATACGAACCCTTTAACA
AAGCGAGCCTGGATTCTCGAAGACTTTAGACCAAATGAAGATATCGCCCCGGTTAAGAGA
GGAAGAAGAAAATTGGAGCGATTTTATGCCCAAGTTGGAAAGCCAGAGGATTCTAAACAC
AGATCATTGTCAGTAGTTATAGAATCGCAAAATTCGGACTACGAATTTGCGTTTGATAAC
TTGAGGAATAGATCAAAATCCCCCCCAGGTTTTGGAAGACTGGATTTTCCCTCCACTCAG
GAAGGGAACGAGGACAAAAAGAAATCCCAGGAAATCATCAGAAGAAAGACAAAATATAGG
TTTTTAATGGCAAGCAATAACAAGATCCCACCGTACGAGAGAGAATATGTATTCAAAAGA
GAACAATTAAATCAAATTGTTGACGATGGATGTTTCTTCTGGAGTGATAAATTATTGCAG
ATATATGCTAGATGTTAA Promoter Sequence
Download FASTA
>SAE2 YGL175C
AGCTTTGCACTTTCTTCTCATTGATCTCATTTTGCTTAGCAAACCATTTTTCTTCAAAGC
CATTTGATCTGTGGACACCGTCCCATCTTGACCCAGGCATAATGGCAAACCTGTTCTCAG
GTGCTGGCTTATCATAAAGCTTGCGGCCCAGTAAAGATGTTTTTACAGTTCTTTCTTTGT
CATGTGTAAATGTTATTGCAGGGTCTTCTATCGTCAGACTCGAGGCAGTTTGATTTTTCT
TCTTATCATGTGCATCTACATTTATTCCAAGCTTTTGCACGTCTCCCATATTCAAATTTT
TCAGGTATTGCTCTCTTTCCGCGGCTTTCTCATCTTCATATTTAGATCGACTAAAACTAG
AATCGTCTATCTTGGAATCTTCCTGAATCTTGTGACCTTGAGCGTCTCTGTATATGGTTT
TTCGTGTTTTCGATTTGTCTGCTACTGTGACAAGTGGCTCTTGAGCCCTGATTTCCTTTA
GATCGTTCTTGCTTTCGTTGCCAGTAATTGACGATGCGGAAGGATGTGTTATTGCATGGG
AAAGCTCGTTTGTTTCCAGGTTCTTCCATATATTCTTGCTTTTTTGTTTGTCAAACTTGC
TGAATGAAGCAACTCCTGACTTCTCCTGTTCTTGTTGCAGTGTACTTAGCCGTTCTTTTA
CTATCAAAGAAGTTTTGTCTGAGTTAGCGTCTGATTTTGACTCTTTCTTCTTCTTTTTCG
TCTTATTTTTGGGTTTCGTGGGCCCATAAGTCTCTGATAAATACTGATGCAATGCCATGT
AATAAACGTCCTGTTGTTATCTTCCACCATTCGAGTCTTGAGAACAACTTTCAAAATCAA
GTCAAATAGCCATTTTCTTTATGCCATTTTCTAAGCGCGTTCTACAAAAAAAAAGCTTTT
AAGCTTTAATACCTTTTTTGTTTACGTTTGCAAACATTGTTATCGTTCACATACCTGCAT
TTCCATCCATGCTGTAAGCCATTAGGTGTTTGTATGTGAG
Chr coordinates
Chr VII from 174322-173285
