Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name ECO1
Systematic Name YFR027W
Alias CTF7
Strain S288c
Description Acetyltransferase; required for establishment of sister chromatid cohesion; acetylates Mps3p to regulate nuclear organization; modifies Smc3p at replication forks and Mcd1p in response to dsDNA breaks; phosphorylated by three kinases (Cdc28p, Cdc7p, Mck1p) to generate pair of phosphates spaced precisely for recognition by ubiquitin ligase SCF-Cdc4; mutations in human homolog ESCO2 cause Roberts syndrome; relative distribution to nucleus increases upon DNA replication stress
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>ECO1 YFR027W
TTTGCCGCGCAGCCTGTGTAAAATGGCGCACACAATCACGTTACTTGAATCTCAGTTCAG
AAGTTTCTTTCAACACAGCCAATTGCATTTAGTCTGCTATGCTTAATATTGTAGCTACTA
CGTGGCAAACATAGCTGCCCGAACTACTTTATGCGTACGTGTCCACAGCAATTTGTATAA
CGACTCAATCAAAATTCTCTCAAACACCTTCATGGGAATCTGTCGACAATGTAATCAGAT
CTCAGCCCAATTGCCAGTATGTGTTCATATCTTATTCCGTGGCCGCCCCTCCAAAAAGCT
TCAAAATACACTCACCAGGCTTACTTCTTGTTGGGAGAAGAACCGTTATCGTTCACTTGA
TAATATTCCTACCAGTATGTTGTCCTATATGGAGTCATGAGCATACATGGTGCAAAATTA
TGGAATTAGCGCAATGAGTTTCAAACAGCAATTTGATCTTTTTATAAACACTGAAATGCC
AGAATTGATAATGTAATAGGAAAAAAAAATGAAAAGATTCAAAACCGAAGATAAAATGAG
ATTATTTTTTTCTTTTATGTAGAAACATCGATTCGCTTCTGTGGGTTCCCATATCCTCGA
GGAGAACTTCTAATATATTCTGTATAATTAATATTATAGCATTAACAACGGTATAATCTC
AGTCATTATCCCAAAATTCACCTATTTTCCCATCATACCGATCTTTGCGAATACTTGAGC
ATGTAAATCAGAGATTCTATGTAACAGCTGCCCAGAAACCAGAAAACGTCTCTTAACCAC
TTCCATTGTTGGCATGTTGAAACCTCCTGCCGCCTTGATCATCCTTCGACTTAGGGAAGA
ATCTTAACAAATGAAATTTAACGTCAACGCGTAATAGAAAAAAAGCCTTTCGCGTACTGT
AATCAGTAATAATACATAAGGAGATGCCAGCTACAACGGACATCAACATATATCTATGTT
TACATATTAGGGTTCAACAGAATATAAATCGTTGCACAAA
Chr coordinates Chr VI from 207452-208297
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