Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name HYP2
Systematic Name YEL034W
Alias eIF-5A, eIF5A, TIF51A
Strain S288c
Description Translation elongation factor eIF-5A; required for translation of proteins containing polyproline stretches, including Bni1p, and this leads to a requirement for mating projection formation; structural homolog of bacterial EF-P; undergoes an essential hypusination modification; HYP2 has a paralog, ANB1, that arose from the whole genome duplication; human EIF5A complements the inviability of the yeast hyp2 anb1 double null mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>HYP2 YEL034W
ATGTCTGACGAAGAACATACCTTTGAAACTGCTGACGCTGGTTCCTCCGCCACCTACCCA
ATGCAATGTTCTGCCTTGAGAAAGAACGGTTTCGTTGTCATCAAGAGTAGACCATGTAAG
ATTGTCGACATGTCCACTTCTAAGACTGGTAAGCACGGTCACGCTAAAGTCCATTTGGTT
GCCATTGATATCTTCACTGGTAAGAAGTTGGAAGATTTGTCTCCATCTACTCACAACATG
GAAGTTCCAGTTGTCAAGAGAAACGAATACCAATTGTTGGACATTGATGACGGTTTCTTG
TCTTTGATGAACATGGACGGTGACACTAAGGATGATGTCAAGGCTCCAGAAGGTGAATTG
GGTGACAGTTTGCAAACTGCTTTTGATGAAGGTAAGGACTTGATGGTTACCATCATCTCC
GCTATGGGTGAAGAAGCCGCCATCTCCTTCAAGGAAGCTGCTAGAACCGATTAA
Promoter Sequence
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>HYP2 YEL034W
GCTGTCTCTACTAACAGATCTTGGCGTTTTTGAATCGTGTAGTTATTTTTATTTATTTTT
TTTATTTCATGTTTTCATGATTTCATCTTACGCAATTTTTTCACGATGAGACAAGGCGGG
CGACCCCACACAAGAGGAAAATTGAACACAATGCGTTGGTAAAGGGATTACGAATTGATT
AAACCAACATAGTGAGACAAGAAAAGAAAAGAAAAGAAAAGGAAAATGAAAAAAAATAAA
AAAAAGAAGGCAACTAGACCAGATGAGCCCGGTTCATTTCTATTCTCTGCAGTCACTGCT
ATTTTCATCAACAGCGCAGGCCAAGTTGAACGAGATAGTAGCAATCGTAAAAGGAACTAG
CTAACTTCATCATGAAAGTTTACCCTTTCTTGCCGCTACCCTTCTCGTTTGGCTGGTATT
AGAGCACAGCGGATATATCCGGCTCAACAGTATAAGTAACGATAAGTCCTGACCATTGGC
TTCGTTCTGGTGGCATTTTCTCTGAGGGGTGAGAACAGCAAAACGGGAACGGCGACTTGG
AGTAGTATAACGCTGTAGCTGGACGCTGAGGGGCCAAGGCCGGTAAAATTCTGCAACACC
CAGACCTTGCTGCAGTGATATCATCCACCCATACCCCTCGATGTATTCCGTAGCGTTATA
TCGGGTCCGTGTGAGGCGACAAGGGACCTCCCGCACCGCACATACCGCAGGAGCTAAAAG
AAACGCCGTCGCCCGAAAAAAAGTTTCGAAGGTGAAGGAACAGTGGTAATAAAAATTTTT
TTCGTCGTCGTCGTCGATCGGCTTTTGGCCGCGTTGATCGTCGTGTTCCACGATTATATA
ATGCACAAGGTTTTTGCCATATCTTGACATTGGAATCCCTCATTTCCTAAATTCCTCTCC
TTCTATCAATTGCTTCCTTTCCTTCTTTCTAACGATTCTACTTCTGTAGCCAATTACTCA
TAGACTCCCAAACACACACAAATACCAACTCATATATACA
Chr coordinates Chr V from 85676-86149
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