Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
NPL3 Systematic Name
YDR432W Alias
MTR13, MTS1, NAB1, NOP3 Strain
S288c Description
RNA-binding protein; promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; represses translation initiation by binding eIF4G; required for pre-mRNA splicing; interacts with E3 ubiquitin ligase Bre1p, linking histone ubiquitination to mRNA processing; may have role in telomere maintenance; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in cytoplasm; protein abundance increases in response to DNA replication stress External sources
Open in SGD
Open in KEGG
Gene Sequence
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>NPL3 YDR432W
ATGTCTGAAGCTCAAGAAACTCACGTAGAGCAACTACCAGAATCTGTTGTCGATGCCCCA
GTCGAAGAACAGCACCAAGAACCACCACAGGCTCCAGATGCTCCACAAGAACCACAAGTT
CCACAGGAATCTGCTCCACAGGAATCTGCTCCACAAGAACCACCAGCTCCACAAGAACAA
AATGACGTTCCTCCACCATCTAATGCTCCAATTTATGAAGGCGAAGAATCCCACAGTGTC
CAAGACTACCAAGAGGCCCACCAGCACCACCAACCACCTGAACCCCAACCATATTATCCT
CCTCCTCCTCCAGGTGAACACATGCACGGTCGCCCACCAATGCACCACCGTCAAGAAGGA
GAACTCTCGAACACCAGATTGTTTGTTAGACCTTTCCCATTGGACGTTCAAGAATCCGAG
TTGAATGAAATCTTTGGTCCATTTGGACCAATGAAGGAAGTCAAGATCTTGAACGGCTTC
GCGTTTGTTGAATTTGAAGAAGCAGAATCCGCTGCCAAAGCCATTGAAGAAGTTCACGGT
AAGAGTTTTGCTAACCAACCTTTGGAAGTTGTTTACTCTAAATTGCCTGCCAAGAGATAC
CGTATCACCATGAAAAACTTACCAGAAGGTTGTTCATGGCAAGATCTTAAAGATTTAGCC
AGGGAAAATAGTTTAGAAACTACTTTTTCTAGCGTCAATACCAGAGATTTTGATGGTACC
GGTGCTCTAGAATTCCCTAGTGAAGAAATCTTGGTCGAAGCTTTGGAGAGATTAAACAAT
ATTGAATTCAGAGGTTCTGTCATTACTGTTGAAAGAGATGACAATCCTCCACCAATCAGA
AGATCAAATAGAGGTGGCTTCAGAGGTCGCGGCGGCTTCAGAGGCGGCTTCAGAGGTGGC
TTCAGAGGCGGTTTCTCCAGAGGCGGCTTCGGTGGCCCCAGAGGTGGATTTGGTGGTCCA
AGAGGTGGTTACGGTGGCTATTCCAGAGGTGGCTACGGTGGCTACTCCAGAGGCGGATAT
GGTGGCTCCAGAGGTGGTTACGATAGTCCTAGAGGTGGTTACGATAGTCCAAGAGGTGGT
TATTCCAGAGGTGGCTATGGTGGTCCAAGAAATGATTACGGTCCTCCAAGAGGTAGCTAC
GGTGGTTCAAGAGGTGGTTATGATGGTCCAAGAGGCGATTATGGTCCTCCAAGAGATGCA
TACAGAACCAGAGATGCTCCACGTGAAAGATCACCAACCAGGTAA Promoter Sequence
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>NPL3 YDR432W
AATCCAAGAGATCGCCGTATCTCAAGTCTGTAATTTTCATAGGATCTCCGCCGGAGTTAT
TCAGGGAAGGATAAATAGACTGTTGAAATTTACTCCAGAAATAGTAATTGGCATTTGATA
TTTGACCTTTCATTTCGTTATAGACAACACCTTTGAAAACAATGTTACTCTCCGGGTCTG
TGATGTTTTTATGCTCCAACCTCCAACCCTCCTGATCAAAATCTTCTTGTTTAAGTAGCG
GATTCAAGGTGGAGTCTAAATAAACACCTCTTAAATTAGCGAAATCTTGAGGGTTCGTAG
TGGAAAAGGGAAAAAATGTATAATCTGGACCTGTCATAGCGTTCATGAAATTAGCTAGAG
ATTTATTTAGCATTTTGAAAAAAGGGTCCCTAACTGGATATTTAACAGACCCACACAACG
TTGTATGCTCTAGAATATGAGGGACCCCAGTGGAATCTGGAGGGTTGGTTTTAAAAGCAA
TGCTGAACACATTATTCTTGTCGTCTCTATCAATATGCAAATGCTCGGCTCCTGTCTGGG
AGTGCACCAAATCTACCGCAGTGAGTCTCAGCTCCGGAACCGGTAGAATTCTTCTCACTT
CATAACCATGGAATATACCTCCAACTGGATATTTTCTAACGGCCTGTGCTTGGGCATACG
AGGACGCAAATCGCTGAAACCGCAACATATATACCGCAGTATATTTTATAGTAACTTTAT
TCTTTTGAGTAGCCTTCTAATTGGTGGCTTATTGATTACAATTGCTTGTTATCATATCTG
TCAATGCTTGTTCAACAATTCAATGATTTACTACTACCTTTATCATAGAGCCCCTCCGTA
TATTTATCACTGTAAACGAAGGGCAAAATTTTTTACATTCTTTTTTTTCGCCACCCAAAG
GGATTTAAAAAGGACATGAGAAAAATAATTTCCTCTCTTCTAAATATATATACTTTTGAA
GGAATCAAAATTAAGCAATTACGCTAAAACCATAAGGATA
Chr coordinates
Chr IV from 1328783-1330027
